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Item Knowledge Regarding Prevention of Nosocomial Infection Among Nurses in a Government Hospital, Chitwan(Tribhuvan University Institute of Medicine, 2014) Gurung, GrishmaTitle: "Knowledge Regarding Prevention of Nosocomial Infection Among Nurses In A Government Hospital, Chitwan." Objective: To find out the knowledge regarding Prevention of Nosocomial Infection among Nurses. Background: Nosocomial infection is an infection developed in favour of hospital environment. It may develop in a hospitalized patient without having been present or incubating at the time of admission or it may be acquired in hospital but only appear after discharge. An infection is considered nosocomial if it becomes evident 48 hours or more after hospital admission or within 30 days of discharge following inpatient care. The mode of transmission and the most frequent types of nosocomial infections are associated with the respiratory tract, blood stream, surgical wounds and urinary tract. For the last 30 years, there has been great interest in understanding the causes and impact of hospital acquired infections. Many experimental studies and randomized trials have examined various methods to prevent nosocomial infections. Research Methodology: Descriptive cross-sectional research design was used. Study was conducted in Bharatpur Government Hospital at Bharatpur, Chitwan. Total of 50 nurses working in the study area were selected as a sample using non- probability, purposive sampling method was used. Self administered structured questionnaire was developed for data collection Result: Results of the study shows that more than three-fourth of the respondents were age of 24-25 years. Most of the respondents respond for hand washing with antiseptic as the important factors of infection prevention. Likewise, most of them respond to know about the responsible organism for nosocomial infection. More than half of the respondents respond hospital acquired pneumonia is the type of most dangerous/deadly nosocomial infection. Cent percent of the respondents viewed on nosocomial infection can be prevented. Likewise, almost all viewed on hand washing can prevent nosocomial infection. Most of them respond incineration as the recommended wastage disposal for preventing infection iiiConclusion: Majority of respondents had not received infection prevention. Most of respondents respond hand washing with antiseptic is the important factors of preventing infection. Cent percent of respondents viewed nosocomial infection can be prevented. Most of respondents respond improper hand washing and prolonged hospitalization are two wide spread causes of nosocomial infection. Most of the respondents respond the needle and sharp instruments are disposed in puncture proof container .most of respondents said syringe are not recapped after its used.