Prevalence of Bacterial and Fungal Agents Causing Lower Respiratory Tract Infections in Patients with Human Immunodeficiency Virus (Hiv) Infection
| dc.contributor.author | Dahal, Sanchita | |
| dc.date.accessioned | 2022-03-22T10:20:49Z | |
| dc.date.available | 2022-03-22T10:20:49Z | |
| dc.date.issued | 2006 | |
| dc.description.abstract | Present study was carried out to study the prevalence of bacterial and fungal agents causing lower respiratory tract infection in HIV infected individuals. LRTI is a common problem among HIV positive patients and majority are due to bacterial infections. A total of 120 HIV infected individuals were included in this study. Gram stain, Ziehl-Neelsen stain and sputum culture were performed. The pattern of microbial distribution on direct microscopic examination was: Gram-positive bacteria-19, Gram-negative bacteria-37, AFB-6 and fungal isolates-36. Sixty-five percent samples showed growth of different bacteria in different culture media. Among them K. pneumoniae (28.6%) was most frequently isolated bacterial pathogen followed by E. coli (17.9%), S. pneumoniae (17.9%), S. aureus (16.1%), AFB (5.0%), P. aeruginosa (8.9%), M. catarrhalis (7.0%) and H. influenzae (3.6%). Among fungal pathogens, most frequently isolated was Candida albicans (44.4%), Aspergillus spp (30.6%) and Penicillium spp (8.3%). Antibiotic susceptibility pattern was examined for bacterial isolates. Among Gram negative bacteria, K. pneumoniae was most sensitive towards chloramphenicol (62.5%) whereas least sensitive towards co-trimoxazole (37.5%). E. coli showed 60% sensitivity towards chloramphenicol and gentamicin whereas 20% sensitivity towards ampicillin. P. aeruginosa was most sensitive towards gentamicin (60%) and least sensitive towards chloramphenicol. M. catarrhalis showed 50% sensitivity towards chloramphenicol, co-trimoxazole and gentamicin whereas 25% sensitivity towards ampicillin and tetracycline. H. influenzae showed 50% sensitivity towards chloramphenicol, ampicillin, gentamicin and tetracycline whereas least sensitive towards co-trimoxazole. S. pneumoniae showed 50% sensitivity towards chloramphenicol, gentamicin and tetracycline whereas 20% sensitivity towards ampicillin. S. aureus showed 55.5% sensitivity towards chloramphenicol, gentamicin,and tetracycline whereas 22.2% sensitivity towards ampicillin. Polymicrobial isolation was also observed. Pneumocystis carinii pneumonia was not documented in our stu | en_US |
| dc.identifier.uri | https://hdl.handle.net/20.500.14540/9328 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Department of Microbiology | en_US |
| dc.subject | HIV infection | en_US |
| dc.subject | Bacterial pathogen | en_US |
| dc.title | Prevalence of Bacterial and Fungal Agents Causing Lower Respiratory Tract Infections in Patients with Human Immunodeficiency Virus (Hiv) Infection | en_US |
| dc.type | Thesis | en_US |
| local.academic.level | Masters | en_US |
| local.institute.title | Central Department of Microbiology | en_US |