Nasal Carriage Rate of Staphylococcus Aureus and MRSA among Health Care Workers in Tertiary Care Center
Date
2017
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Faculty of Microbiology
Abstract
Staphylococcus aureus is a gram positive bacterium responsible for several
bacterial infections. S. aureus especially methicillin-resistant S. aureus
(MRSA), are usually resistant to several antibiotics which is a global public
health problem, associated with considerable mortality and morbidity
worldwide. Methicillin-resistant Staphylococcus aureus continues to be an
important nosocomial pathogen and infections are often difficult to manage due
to its resistance to multiple antibiotics. Healthcare workers are important source
of nosocomial transmission of MRSA.
This study aimed to determine the frequency of staphylococcal nasal carriage
of health care workers (HCWs) and antimicrobial susceptibility profile of the
isolates in Gandaki Medical College and Research Centre Pvt. Ltd, Pokhara.
The study was conducted in altogether 288 samples. For isolation and
identification of MRSA culture and different biochemical tests were performed.
Out of 58 (20.14%) S. aureus isolated 18.97% are MRSA, more MRSA was
noticed in female (19.15%) than male (18.18%). However, there is no
significant association between gender and MRSA (p=0.723). The prevalence
of nasal carrier MRSA is 3.82%. Hence, it was concluded that prevalence of
MRSA still emerging. Nasal carriage of S. aureus and MRSA among HCWs
necessitates the need of control in the frequency of their exposure with the
vulnerable patients and need of strict infection control measures to be followed
to control the nosocomial infections. The results emphasize the need for high
standards of infection control in tertiary care. Vancomycin and Amikacin was
found to be most effective (100%) against Methicillin-Resistant S. aureus.
Description
Keywords
Nasal carriage, Antimicrobial, Health care workers, MRSA