Analisys of Bioactive Phytochemicals and Study of Antimicrobial Activity From Methanolic Extract of Roots of Streptopus streptopoides
Date
2024-06
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Publisher
Institute of Science & Technology
Abstract
Traditional practice of using medicinal plants have been the foundation of modern medicine. Streptopus streptopoides is a plant of traditional medicinal value. This report focuses in the phytochemical analysis of root parts of Streptopus streptopoides collected from Gorkha and study of biological activity of the extract. Methanolic extract of root was used for the analysis. Herein, three hundred grams of dried powder of the root of the plant was processed to extraction using methanol. The extract of S. streptopoides root solution was subjected to primary phytochemical screening. Methanol extract method revealed the presence of various phytochemicals. Total flavonoid content (TFC) in methanol has been reported to be 1.92±0.36 mg QE/g. It indicated the prescence of very low content of flavonoid in the plant sample. The total phenolic content (TPC) in methanol extract has been quantified to be 50.37 ± 0.44 mg GAE/g. Nauplii started dying at the concentration of 50 ppm. 50% (or more) of the tested nauplli died at the highest concentration of 100 ppm. Hence, LC50 of methanol extract is at 100 ppm (100 µg/mL).
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Keywords
Streptopus streptopoides, phytochemical screening, alkaloids, Flavonoid, nauplii