Sero-Epidemiological Study of Dengue Virus in Some Hospitals of Nepal

dc.contributor.authorKuikel, Dharma Prasad
dc.date.accessioned2022-12-14T05:27:49Z
dc.date.available2022-12-14T05:27:49Z
dc.date.issued2011
dc.description.abstractDengue is an emerging mosquito-borne viral disease in the world and is the serious public health problem of Nepal. This study was designed to determine sero-epidemiology of dengue virus infection during the period (June-Nov) of 2010 among suspected patients with fever visiting Koshi Zonal Hospital (KZH), Biratnagar, Narayani sub-regional Hospital (NSH), Birgunj, Sukraraj Tropical and Infections Disease Hospital(STIDH), Kathmandu and Dhading District Hospital (DDH), Dhading beshi. The sero-prevalence of anti-dengue IgM antibody was determined by enzyme linked immunosorbent assay (ELISA). Among 271 serum samples tested, the anti-dengue IgMpositivity was 14.4%. Sero-positivity in male was 10.7% of total and that in female was3.7%. Among different age groups, the highest positive cases (11.8%) were from agegroup 15-50 years and found least among the age group above 50 years (0.4%). Out of 4different hospitals, the highest positive cases were from STIDH with 9.2% and the least positive cases were from DDH (0.4%). The distribution of dengue positive cases among different occupation group was highest in students (5.9%) having least positivity among others and labour groups (0.4%). RT-PCR showed 4.7% positivity of 21 samples tested. Key words: dengue fever, epidemiology, IgM Capture ELISA, RT-PCR.en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14540/13710
dc.language.isoen_USen_US
dc.publisherDepartment of Microbiologyen_US
dc.subjectDengue feveren_US
dc.subjectEpidemiologyen_US
dc.subjectIgM Capture ELISAen_US
dc.subjectRT-PCR.en_US
dc.titleSero-Epidemiological Study of Dengue Virus in Some Hospitals of Nepalen_US
dc.typeThesisen_US
local.academic.levelMastersen_US
local.institute.titleCentral Department of Microbiologyen_US

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